This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Caspase recruitment domain-containing protein 9.
monocytogenes. Likely controls various innate immune response pathways depending on the intracellular pathogen.
Human | |
---|---|
Gene Name: | CARD9 |
Uniprot: | Q9H257 |
Entrez: | 64170 |
Belongs to: |
---|
No superfamily |
CANDF2; CARD9; caspase recruitment domain family, member 9; caspase recruitment domain-containing protein 9; hCARD9
Mass (kDA):
62.241 kDA
Human | |
---|---|
Location: | 9q34.3 |
Sequence: | 9; NC_000009.12 (136363956..136373669, complement) |
Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Cytoplasm.
PMID: 11053425 by Bertin J., et al. CARD9 is a novel caspase recruitment domain-containing protein that interacts with Bcl10/CLAP and activates NF-kappa B.
PMID: 19864672 by Glocker E.-O., et al. A homozygous CARD9 mutation in a family with susceptibility to fungal infections.