Caspase recruitment domain-containing protein 17 (CARD17)

Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its launch during inflammation. Inhibits the release of IL1B in response to LPS in monocytes.

However, unlike CASP1, don't induce NF-kappa-B activation. .