Calpain-5 Antibodies

AND CAPN5 ELISA kits, Calpain-5 Proteins

Many biological assays use antibodies to detect Calpain-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calpain-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calpain-5 antibodies...

We validate the specificity of these antibodies to Calpain-5 by testing them on tissues known to express CAPN5 positively and negatively. Browse below to find the CAPN5 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CAPN5 Infographic by Boster Bio

All CAPN5 Products

Product

Figures

Specificity

Applications

Price

Anti-Calpain-5 CAPN5 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A08350
100ul

Anti-Calpain 5 (CAPN5) Mouse Monoclonal Antibody [Clone ID: OTI4H5]

Human, Mouse, Rat

$523
Cat # M08350-1
100 µl

Anti-Calpain 5 (CAPN5) Mouse Monoclonal Antibody [Clone ID: OTI7D2]

Human, Mouse, Rat

IHC

$523
Cat # M08350
100 µl

Calpain 5 (CAPN5) (NM_004055) Human Over-expression Lysate

Human

$628
Cat # LS000726
100 µg

Anti-CAPN5 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A08350-1
100 µg/vial

CAPN5 Overview

Facts about Calpain-5.

CAPN5 3D structure. Source: alphafold

Calpain-5 (CAPN5)

Calcium-regulated non-lysosomal thiol-protease. .

Gene Information

Human
Gene Name:	CAPN5
Uniprot:	O15484
Entrez:	726

Family

Belongs to:

peptidase C2 family

Alternative Names

calpain 5; Calpain htra-3; calpain-5; EC 3.4.22; EC 3.4.22.54; FLJ46245; HTRA3NCL3; nCL-3EC 3.4.22.-; New calpain 3

Molecular Weight

Mass (kDA):
73.169 kDA

Genomic Context


Human

Location:	11q13.5
Sequence:	11; NC_000011.10 (77066971..77126155)

Tissue Specificity

Expressed in many tissues. Strong expression in the photoreceptor cells of the retina, with a punctate pattern of labeling over the nuclei and inner segments with less expression along the other segments and outer plexiform layer.

Diseases

Malignant Neoplasms
Obesity
Polycystic Ovary Syndrome
Neoplasms
Pathologic Neovascularization
Retinal Neovascularization
Uveitis
Diabetes Mellitus
Autoimmune Diseases
Hypertensive Disease
Diabetes Mellitus, Non-insulin-dependent
Autoimmune Reaction

Retinal Degeneration
Neurodegenerative Disorders
Endometrial Polyp
Carcinoma, Papillary
Cardiac Complication
Inflammatory Response
Carcinoma

Pathways

Hair Cycle
Cell Death
Proteolysis
Anagen
Cell Growth
Sex Determination
Wound Healing
Pathogenesis

Meiosis
Localization
Inflammatory Response

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPN5

References

PMID: 9367857 by Mugita N., et al. Identification of a novel, tissue-specific calpain htra-3; a human homologue of the Caenorhabditis elegans sex determination gene.

PMID: 9339374 by Dear T.N., et al. A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution.