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CAMK1D Antibodies
AND CAMK1D ELISA kits, CAMK1D Proteins
Many biological assays use antibodies to detect CAMK1D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAMK1D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAMK1D antibodies...
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CAMK1D Infographic by Boster Bio
All CAMK1D Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M05050
100 µl
Cat # M05050
100 µl
CAMK1D Overview
Facts about Calcium/calmodulin-dependent protein kinase type 1D.
Calcium/calmodulin-dependent protein kinase type 1D (CAMK1D)
Calcium/calmodulin-dependent protein kinase that works from the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic development of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst.
Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | CAMK1D |
| Uniprot: | Q8IU85 |
| Entrez: | 57118 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
calcium/calmodulin-dependent protein kinase ID; calcium/calmodulin-dependent protein kinase type 1D; CaM kinase I delta; CaM kinase ID; CaM-K1; CaMKI delta; CaM-KI delta; CaMKID; CaMKI-like protein kinase; CKLiKEC 2.7.11.17; EC 2.7.11
Molecular Weight
Mass (kDA):
42.914 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10p13 |
| Sequence: | 10; NC_000010.11 (12349514..12835545) |
Tissue Specificity
Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
Subcellular Localizations
Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Insulin Resistance
- Insulin Sensitivity
- Carcinoma
- Malignant Neoplasm Of Breast
- Malignant Neoplasms
- Mammary Neoplasms
- Tissue Adhesions
- Obesity
- Prediabetes Syndrome
- Embryonal Carcinoma
- Campomelic Dysplasia
Pathways
- Insulin Secretion
- Secretion
- Respiratory Burst
- Pathogenesis
- Cell Proliferation
- Cell Migration
- Chemotaxis
- Phagocytosis
PTMs
- Phosphorylation
Research Areas
- Protein Kinase
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAMK1D
bosterbio.com/bosterbio-gene-info-cards/CAMK1D
References
PMID: 11050006 by Verploegen S., et al. Identification and characterization of CKLiK, a novel granulocyte Ca++/calmodulin-dependent protein kinase.
PMID: 12935886 by Ishikawa Y., et al. Identification and characterization of novel components of a Ca2+/calmodulin-dependent protein kinase cascade in HeLa cells.