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- Table of Contents
Facts about Cactin.
Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development.
Human | |
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Gene Name: | CACTIN |
Uniprot: | Q8WUQ7 |
Entrez: | 58509 |
Belongs to: |
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CACTIN family |
C19orf29; cactin homolog; cactin; cactin, spliceosome C complex subunit; chromosome 19 open reading frame 29; FLJ17482; FLJ59622; fSAPc; functional spliceosome-associated protein c; NY REN 24 antigen; NY-REN-24 antigen; NY-REN-24
Mass (kDA):
88.702 kDA
Human | |
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Location: | 19p13.3 |
Sequence: | 19; NC_000019.10 (3610645..3626815, complement) |
Nucleus. Cytoplasm, cytosol. Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus.
PMID: 20829348 by Atzei P., et al. Cactin targets the MHC class III protein IkappaB-like (IkappaBL) and inhibits NF-kappaB and interferon-regulatory factor signaling pathways.