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Carbonic anhydrase 12 Antibodies
AND CA12 ELISA kits, Carbonic anhydrase 12 Proteins
Many biological assays use antibodies to detect Carbonic anhydrase 12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Carbonic anhydrase 12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Carbonic anhydrase 12 antibodies...
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CA12 Infographic by Boster Bio
All CA12 Products
Product
Figures
Specificity
Applications
Price
Anti-CA12/Ca Xii Antibody
5 Q&As
Human, Mouse, Rat
ELISA, IHC-P, WB, IF (paraffin)
$335
Cat # A30588
100ul
Cat # A30588
100ul
Human
ELISA
$750
Cat # EK1942
96 wells/kit, with removable strips.
Cat # EK1942
96 wells/kit, with removable strips.
Mouse
ELISA
$750
Cat # EK1833
96 wells/kit, with removable strips.
Cat # EK1833
96 wells/kit, with removable strips.
Human
Flow Cytometry, WB
$523
Cat # M04063-2
100 µl
Cat # M04063-2
100 µl
CA12 Overview
Facts about Carbonic anhydrase 12.
Carbonic anhydrase 12 (CA12)
Reversible hydration of carbon dioxide. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CA12 |
| Uniprot: | O43570 |
| Entrez: | 771 |
Family
| Belongs to: |
|---|
| alpha-carbonic anhydrase family |
Alternative Names
CA12; Carbonate dehydratase XII; carbonic anhydrase 12; Carbonic Anhydrase XII; carbonic anhydrase XIICAXII; carbonic dehydratase; CA-XII; EC 4.2.1.1; FLJ20151; HsT18816; Tumor antigen HOM-RCC-3.1.3
Molecular Weight
Mass (kDA):
39.451 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q22.2 |
| Sequence: | 15; NC_000015.10 (63321378..63382110, complement) |
Tissue Specificity
Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis.
Subcellular Localizations
Membrane; Single-pass type I membrane protein. Cell membrane.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Hypoxia
- Neoplasm Metastasis
- Kidney Neoplasm
- Renal Cell Carcinoma
- Malignant Paraganglionic Neoplasm
- Mammary Neoplasms
- Uterine Cervical Neoplasm
- Malignant Neoplasm Of Breast
- Malignant Tumor Of Cervix
- Cell Invasion
Pathways
- Secretion
- Reverse Transcription
- Nitrogen Fixation
- Conjugation
- Pathogenesis
- Transport
- Cell Growth
- Cell Adhesion
- Stem Cell Differentiation
- Spermatogenesis
- Bicarbonate Transport
- Gene Conversion
- Cell Cycle
PTMs
- Nitration
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CA12
bosterbio.com/bosterbio-gene-info-cards/CA12
References
PMID: 9636197 by Tuereci O., et al. Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers.
PMID: 9770531 by Ivanov S.V., et al. Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes.