This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Carbonic anhydrase-related protein 10.
Human | |
---|---|
Gene Name: | CA10 |
Uniprot: | Q9NS85 |
Entrez: | 56934 |
Belongs to: |
---|
alpha-carbonic anhydrase family |
CA10; Carbonic Anhydrase X; carbonic anhydrase-related protein 10; Carbonic anhydrase-related protein X; CARP X; CARPX; CA-RPX; CARPXCA-RP X; Cerebral protein 15; cerebral protein-15; HUCEP-15
Mass (kDA):
37.563 kDA
Human | |
---|---|
Location: | 17q21.33-q22 |
Sequence: | 17; NC_000017.11 (51630313..52160017, complement) |
Strong expression in brain and central nervous system.
Steven Boster has a series on his website that addresses the use of Anti–CAh20 antibodies. He explains why high-affinity antibodies are important and how they can work in clinical trials. He also discusses his journey to create the CA10 marker. This information can be used by scientists around the globe. You may also be interested learning more about his history and the products he offers.
Boster Bio Anti CAh20 Antibody can be used to conduct research on antibodies against CAh20. This antibody reacts well with human, mouse, rat proteins in ELISA, and WB assays. The boster antigen has been extensively cited in scientific literature due to its high affinity and selectivity. The boster antibodies are highly respected in the research community. The boster bio Anti CAh20 antibody is readily available at affordable prices. Don't hesitate to order it!
Boster Bio, a top manufacturer of picogram sensitivity ELISA tests and IHC-optimized polyclonal antibodies, is the manufacturer. The Boster Bio catalog contains over 12,000 antibodies with high affinity. Each antibody has been tested against 250 tissue samples to confirm its specificity. The boster bio antibody is quantitatively tested against untransfected cells as well as recombinant proteins.
High-affinity primary antibody are distinguished by their specificity for the epitope that they recognize. They are available as polyclonal and monoclonal antibodies, and they are commonly used for detecting and measuring specific biomolecules. GenScript stocks over 1000 monoclonal, and polyclonal highly specific antibodies in all major fields of life-science research. Each antibody has been tested in at least two applications to ensure high levels of specificity and sensitivity.
A polyclonal antibodies is a mixture of multiple B cell clones. Each binds to a particular epitope with different specificities. They are less effective in recognizing target proteins because they cross-react with nonspecific molecules. High-affinity primary antibodies are obtained by antigen affinity purification and use the CA10 marker to identify the epitope. This method involves passing polyclonal antrum through an affinity column containing immobilized antibodies. Any non-specific antibody are then removed from the column.
False-positive staining, another issue with immunomimetic combinations, is another. When the antibody detects an immunogen that has an immunization-specific epitope, it causes a false-positive signal. This is a common problem and requires careful consideration. This should not only be the CA10 marker. The antibodies should also be raised against an immunogen evolutionarily dissimilar from the target species.
The quality of the staining depends on the concentration of the primary antibody, the diluent, the incubation time, and the temperature. Each sample should be incubated at the same temperature and time. Also, ensure the incubation time is consistent. It's best to test the samples in a variety concentrations, especially if it's brand new. You must decide on the best solution.
Although there are several commercial sources of primary antibodies, their quality can vary, so it's important to ensure you're purchasing the best quality possible. The quality of your antibody can make or ruin the success of your experiment. Make sure you get the best quality. If you're unsure, contact the manufacturer directly. They can offer technical support and assistance as well as support. You can get the best results by purchasing the antibodies directly from their manufacturer.
The tumor-specific marker CA10 has been identified in breast cancer. These mRNAs have also been shown to undergo methylation during breast cancergenesis. The CA10 marker was also found to be hypermethylated in urine, potentially indicating a risk for bladder cancer. Additionally, marginally elevated breast cancer risks were associated with CA10 methylation in the leukocyte DNA, even after PS adjustment. This study aimed to confirm the results using an amplified sequence consisting of seven CpGs in the second exon of CA10, but an external validation dataset only included two CpG probes and was not statistically significant.
Further, the luminal B subtype of breast cancer was associated with CA10methylation. WT1 methylation was found to be associated with a higher chance of developing luminal a or b breast cancer. Therefore, the CA10 marker could be used to detect breast cancer more accurately. But the potential risks of cancer arising from this methylation is yet to be fully understood.
Several studies have investigated the functional characterization of the CA10 marker and its clinical utility. However, further studies are needed in order to confirm its clinical usefulness. Moreover, the CA10 marker has not been used in many countries as of yet, but its utility in predicting the recurrence of bladder cancer is unclear. The CA10 marker, which is one of many emerging biomarkers to detect bladder cancer, is only one. However, its use will likely increase as new biomarkers emerge.
The CA10 marker has been widely used in the treatment and prevention of pancreatic tumors. The tumor marker is a valuable diagnostic tool, but it is not always a reliable biomarker. The CA10 marker is a better indicator of early cancers than the Urokinase Plasminogen Activator. Although the CA10 marker is an emerging tumor-specific mRNA, it has not been shown to be highly sensitive in detecting occult recurrence.
Steve Boster, in his final book The CA10 Marker, reveals how to use this marker to your business. Boster also offers great tips to increase your sales. You should never pay for advertising that doesn’t deliver results. Instead, you should focus on attracting targeted clients and you will immediately see an increase in sales.
PMID: 11311946 by Okamoto N., et al. cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain.
PMID: 9921901 by Kleiderlein J.J., et al. CCG repeats in cDNAs from human brain.