C4BPB Antibodies

AND C4BPB ELISA kits, C4BPB Proteins

Many biological assays use antibodies to detect C4BPB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C4BPB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C4BPB antibodies...

We validate the specificity of these antibodies to C4BPB by testing them on tissues known to express C4BPB positively and negatively. Browse below to find the C4BPB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C4BPB Infographic by Boster Bio

All C4BPB Products

Product

Figures

Specificity

Applications

Price

Anti-C4b-binding protein beta chain C4BPB Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A08320
100ul

C4BPB (NM_001017365) Human Recombinant Protein

$1249
Cat # PROTP20851
20 µg

Anti-C4 binding protein Rabbit Monoclonal Antibody

Human, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M08320
100 μl/vial

C4BPB Overview

Facts about C4b-binding protein beta chain.

C4BPB 3D structure. Source: alphafold

C4b-binding protein beta chain (C4BPB)

Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b.

It also hastens the degradation of the C4bC2a complicated (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component.

Gene Information

Human
Gene Name:	C4BPB
Uniprot:	P20851
Entrez:	725

Family

Belongs to:

No superfamily

Alternative Names

C4b binding protein, beta chain; C4b-binding protein beta chain; C4BP; complement component 4 binding protein, beta chain; complement component 4 binding protein, beta; complement component 4-binding protein, beta

Molecular Weight

Mass (kDA):
28.357 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (207088795..207099993)

Subcellular Localizations

Secreted.

Diseases

Liver Carcinoma
Hemolysis (disorder)
Protein S Deficiency
Thrombosis
Measles
Proteinuria Of Undiagnosed Cause
Thrombophilia
Pre-eclampsia
Venous Thrombosis
Hypertensive Disease

Edema
Lupus Erythematosus, Systemic
Liver Neoplasms
Alzheimer's Disease

Pathways

Complement Activation
Coagulation
Cytolysis
Pathogenesis
Localization
Excretion

PTMs

Hydroxylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C4BPB

References

PMID: 8325877 by Hillarp A., et al. The human C4b-binding protein beta-chain gene.

PMID: 2300577 by Hillarp A., et al. Cloning of cDNA coding for the beta chain of human complement component C4b-binding protein: sequence homology with the alpha chain.