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- Table of Contents
1 Q&As
Facts about Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1.
Plays a role in the reorganization of the actin cytoskeleton in response to fungal infection. .
Human | |
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Gene Name: | BAIAP2L1 |
Uniprot: | Q9UHR4 |
Entrez: | 55971 |
Belongs to: |
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No superfamily |
BAI1-associated protein 2-like 1; BAI1-associated protein 2-like protein 1; brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; FLJ42275; IRTKSInsulin receptor tyrosine kinase substrate
Mass (kDA):
56.883 kDA
Human | |
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Location: | 7q21.3-q22.1 |
Sequence: | 7; NC_000007.14 (98291650..98401090, complement) |
Cytoplasm, cytoskeleton. Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
PMID: 17430976 by Millard T.H., et al. Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties.
PMID: 19366662 by Vingadassalom D., et al. Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation.