BAALC Antibodies

AND BAALC ELISA kits, BAALC Proteins

Many biological assays use antibodies to detect BAALC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BAALC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BAALC antibodies...

We validate the specificity of these antibodies to BAALC by testing them on tissues known to express BAALC positively and negatively. Browse below to find the BAALC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BAALC Infographic by Boster Bio

All BAALC Products

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Product

Figures

Specificity

Applications

Price

Human BAA Recombinant Protein

SDS-PAGE

$300
Cat # PROTQ8WXS3
Starting from 20ug

BAALC (NM_024812) Human Over-expression Lysate

Human

$628
Cat # LS079870
100 µg

BAALC Overview

Facts about Brain and acute leukemia cytoplasmic protein.

BAALC 3D structure. Source: alphafold

Brain and acute leukemia cytoplasmic protein (BAALC)

May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A. .

Gene Information

Human
Gene Name:	BAALC
Uniprot:	Q8WXS3
Entrez:	79870

Family

Belongs to:

No superfamily

Alternative Names

brain and acute leukemia cytoplasmic protein; brain and acute leukemia, cytoplasmic; FLJ12015

Molecular Weight

Mass (kDA):
19.224 kDA

Genomic Context


Human

Location:	8q22.3
Sequence:	8; NC_000008.11 (103140725..103230305)

Tissue Specificity

Predominantly expressed in neuroectoderm- derived tissues. Expressed in the brain and spinal cord, and at low levels, in the adrenal gland. In the bone marrow, confined to the CD34+ progenitor cells. Not found in peripheral blood mononuclear cells, nor lymph nodes. Tends to be expressed at high levels in acute myeloid leukemia and glioblastoma cells.

Subcellular Localizations

Cytoplasm. Cell junction, synapse, synaptosome. Membrane raft. Cell junction, synapse, postsynaptic density. In neurons, localizes to postsynaptic lipid rafts (By similarity). In myocardial and skeletal muscle cells, localizes to the cytoplasm adjacent to the inner cell membrane, polarized to one end of the myocyte (By similarity).

Diseases

Leukemia
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Acute Leukemia
Malignant Neoplasms
Cytogenetic Abnormality
Neoplasms
Acute Lymphocytic Leukemia
Flt3 Internal Tandem Duplication
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Adult Acute Myeloblastic Leukemia
Leukemogenesis

Neoplasm, Residual
Malignant Paraganglionic Neoplasm
Nephroblastoma
Cell Transformation, Neoplastic
Melanoma
Childhood Acute Myeloid Leukemia
Chromosomal Translocation

Pathways

Pathogenesis
Localization
Drug Resistance
Translation
Transport
Cell Dedifferentiation
Cell Proliferation
Osteoblast Differentiation
Electron Transport
Brain Development
Electron Transport Chain
Dna Methylation

Methylation
Dna Amplification
System Development
Cell Death
Cell Differentiation
Dedifferentiation
Oncogenesis

PTMs

Methylation
Phosphorylation

Acetylation
Palmitoylation

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BAALC

References

PMID: 11707601 by Tanner S.M., et al. BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.