RPAP2 Antibodies

AND RPAP2 ELISA kits, RPAP2 Proteins

Many biological assays use antibodies to detect RPAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RPAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RPAP2 antibodies...

We validate the specificity of these antibodies to RPAP2 by testing them on tissues known to express RPAP2 positively and negatively. Browse below to find the RPAP2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RPAP2 Infographic by Boster Bio

All RPAP2 Products

Product

Figures

Specificity

Applications

Price

Anti-RPAP2 Antibody

4 Q&As

Human

$399
Cat # A09543
100μl

RPAP2 (NM_024813) Human Over-expression Lysate

Human

$628
Cat # LS079871
100 µg

RPAP2 Overview

Facts about Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2.

RPAP2 3D structure. Source: alphafold

Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (RPAP2)

Protein phosphatase that shows CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

Gene Information

Human
Gene Name:	RPAP2
Uniprot:	Q8IXW5
Entrez:	79871

Family

Belongs to:

RPAP2 family

Alternative Names

C1orf82putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; chromosome 1 open reading frame 82; EC 3.1.3.-; FLJ13150; RNA polymerase II associated protein 2; RNA polymerase II-associated protein 2

Molecular Weight

Mass (kDA):
69.509 kDA

Genomic Context


Human

Location:	1p22.1
Sequence:	1; NC_000001.11 (92299050..92402056)

Subcellular Localizations

Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner.

Diseases

Acute Pancreatitis
Pancreatitis
Inflammation
Lung Injury
Acute Lung Injury

Interacting Proteins

PIH1D1
RPRD1B

Pathways

Cytokine Production
Cytokine Secretion
Rna Processing
Secretion

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RPAP2

References

PMID: 17643375 by Jeronimo C., et al. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

PMID: 22231121 by Ni Z., et al. Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B.