BUB3 Antibodies

AND BUB3 ELISA kits, BUB3 Proteins

Many biological assays use antibodies to detect BUB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BUB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BUB3 antibodies...

We validate the specificity of these antibodies to BUB3 by testing them on tissues known to express BUB3 positively and negatively. Browse below to find the BUB3 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BUB3 Infographic by Boster Bio

All BUB3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Bub3 Antibody Picoband®

3 Q&As

Human, Mouse, Rat

IHC, IHC-F, ICC, WB

$370
Cat # PA1645
100 μg/vial

Anti-BUB3 (H274) Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A03118
100ul

Anti-Bub3 Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$405
Cat # A03118-1
100ul

BUB3 (NM_001007793) Human Recombinant Protein

$813
Cat # PROTO43684
20 µg

Anti-BUB3 Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03118-2
100 μg/vial

Anti-Bub3 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M03118-1
100 μl/vial

BUB3 (NM_004725) Human Over-expression Lysate

Human

$628
Cat # LS009184
100 µg

BUB3 Overview

Facts about Mitotic checkpoint protein BUB3.

BUB3 3D structure. Source: alphafold

Mitotic checkpoint protein BUB3 (BUB3)

Has a double role in spindle-assembly checkpoint signaling and in promoting the establishment of proper kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments.

Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis.

Gene Information

Human
Gene Name:	BUB3
Uniprot:	O43684
Entrez:	9184

Family

Belongs to:

WD repeat BUB3 family

Alternative Names

BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog; BUB3 budding uninhibited by benzimidazoles 3 homolog; Bub3; BUB3L; budding uninhibited by benomyl; budding uninhibited by benzimidazoles 3 homolog (yeast); hBUB3; mitotic checkpoint component; mitotic checkpoint protein BUB3

Molecular Weight

Mass (kDA):
37.155 kDA

Genomic Context


Human

Location:	10q26.13
Sequence:	10; NC_000010.11 (123154244..123170467)

Subcellular Localizations

Nucleus. Chromosome, centromere, kinetochore. Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition.

Diseases

Malignant Neoplasms
Neoplasms
Aneuploidy
Carcinoma
Cell Transformation, Neoplastic
Instabilities, Chromosomal
Malignant Neoplasm Of Breast
Mammary Neoplasms
Genomic Instability
Polyploidy
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Lung
Cytogenetic Abnormality

Carcinogenesis
Leukemia
Liver Carcinoma
Tetraploidy
Malignant Tumor Of Colon
Liver Neoplasms
Melanoma

Interacting Proteins

BUB1
BUB1B
PSTPIP1

Pathways

Anaphase
Spindle Checkpoint
Mitosis
Spindle Assembly
Spindle Assembly Checkpoint
Cell Cycle
Chromosome Segregation
Metaphase
Localization
Kinetochore Localization
Cell Division
Interphase
Meiosis

Cell Cycle Arrest
Dna Replication
Proteolysis
Cytokinesis
Prophase
Dna Repair
Transport

PTMs

Phosphorylation
Ubiquitination

Cleavage
Dephosphorylation

Methylation

Research Areas

Cell Cycle and Replication
Core ESC-Like Genes
DNA Repair
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BUB3

References

PMID: 10198256 by Seeley T.W., et al. Phosphorylation of human MAD1 by the BUB1 kinase in vitro.

PMID: 9660858 by Taylor S.S., et al. The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase.