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- Table of Contents
Facts about RalBP1-associated Eps domain-containing protein 2.
Human | |
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Gene Name: | REPS2 |
Uniprot: | Q8NFH8 |
Entrez: | 9185 |
Belongs to: |
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No superfamily |
partner of Ral-binding protein 1; POB1Partner of RalBP1; RALBP1 associated Eps domain containing 2; ralBP1-associated Eps domain-containing protein 2; RalBP1-interacting protein 2
Mass (kDA):
71.534 kDA
Human | |
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Location: | Xp22.2 |
Sequence: | X; NC_000023.11 (16946658..17220724) |
Expressed at high levels in the cerebrum, cerebellum, lung, kidney, and testis. Weakly expressed in the kidney. Relatively highly expressed in androgen-dependent as compared to androgen-independent prostate cancer cell lines and xenografts. Isoform 2 is down-regulated during progression of prostate cancer.
Cytoplasm.
PMID: 9422736 by Ikeda M., et al. Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral.
PMID: 12771942 by Oosterhoff J.K., et al. REPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cells.