BCO1 Antibodies

AND BCO1 ELISA kits, BCO1 Proteins

Many biological assays use antibodies to detect BCO1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BCO1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BCO1 antibodies...

We validate the specificity of these antibodies to BCO1 by testing them on tissues known to express BCO1 positively and negatively. Browse below to find the BCO1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BCO1 Infographic by Boster Bio

All BCO1 Products

Product

Figures

Specificity

Applications

Price

Anti-BCMO1 BCO1 Antibody

Human, Mouse, Rat

$405
Cat # A07016
100ul

BCMO1 (BCO1) (NM_017429) Human Over-expression Lysate

Human

$960
Cat # LS053630
100 µg

BCO1 Overview

Facts about Beta,beta-carotene 15,15'-dioxygenase.

BCO1 3D structure. Source: alphafold

Beta,beta-carotene 15,15'-dioxygenase (BCO1)

Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism. .

Gene Information

Human
Gene Name:	BCO1
Uniprot:	Q9HAY6
Entrez:	53630

Family

Belongs to:

carotenoid oxygenase family

Alternative Names

Beta,beta-carotene 15,15'-dioxygenase

Molecular Weight

Mass (kDA):
62.637 kDA

Genomic Context


Human

Location:	16q23.2
Sequence:	16; NC_000016.10 (81238448..81291142)

Tissue Specificity

Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon.

Diseases

Hypercarotenemia and vitamin A deficiency, autosomal dominant (HCVAD)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCO1

References

PMID: 11401432 by Yan W., et al. Cloning and characterization of a human beta,beta-carotene-15,15- prime dioxygenase that is highly expressed in the retinal pigment epithelium.

PMID: 24668807 by dela Sena C., et al. The human enzyme that converts dietary provitamin A carotenoids to vitamin A is a dioxygenase.