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- Table of Contents
Facts about Branched-chain-amino-acid aminotransferase, cytosolic.
Human | |
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Gene Name: | BCAT1 |
Uniprot: | P54687 |
Entrez: | 586 |
Belongs to: |
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class-IV pyridoxal-phosphate-dependent aminotransferase family |
BCAT(c); BCAT1; BCAT-1; BCATC; BCT1; BCT1PNAS121; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; branched-chain-amino-acid aminotransferase, cytosolic; DKFZp686E12175; EC 2.6.1.42; ECA39; MECA39; placental protein 18; PNAS121; PP18; Protein ECA39
Mass (kDA):
42.966 kDA
Human | |
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Location: | 12p12.1 |
Sequence: | 12; NC_000012.12 (24810024..24949101, complement) |
During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.
Cytoplasm.
PMID: 8692959 by Schuldiner O., et al. ECA39, a conserved gene regulated by c-Myc in mice, is involved in G1/S cell cycle regulation in yeast.
PMID: 16141215 by Goto M., et al. Structural determinants for branched-chain aminotransferase isozyme- specific inhibition by the anticonvulsant drug gabapentin.