BARD1 Antibodies

AND BARD1 ELISA kits, BARD1 Proteins

Many biological assays use antibodies to detect BARD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BARD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BARD1 antibodies...

We validate the specificity of these antibodies to BARD1 by testing them on tissues known to express BARD1 positively and negatively. Browse below to find the BARD1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BARD1 Infographic by Boster Bio

All BARD1 Products

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Specificity

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Price

Anti-BARD1 Antibody

3 Q&As

Human

$360
Cat # A01646
100 µl

Anti-BARD1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A01646-2
100 μg/vial

BARD1 Overview

Facts about BRCA1-associated RING domain protein 1.

BARD1 3D structure. Source: alphafold

BRCA1-associated RING domain protein 1 (BARD1)

E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of'Lys-6'-linked polyubiquitin chains and coordinates a wide range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability.

Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that's required for its tumor suppressor function.

Gene Information

Human
Gene Name:	BARD1
Uniprot:	Q99728
Entrez:	580

Family

Belongs to:

No superfamily

Alternative Names

BARD-1; BRCA1 associated RING domain 1; BRCA1-associated RING domain gene 1; BRCA1-associated RING domain protein 1; EC 6.3.2.-

Molecular Weight

Mass (kDA):
86.648 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (214725645..214809683, complement)

Subcellular Localizations

Nucleus. During S phase of the cell cycle, colocalizes with BRCA1 into discrete subnuclear foci. Can translocate to the cytoplasm. Localizes at sites of DNA damage at double-strand breaks (DSBs); recruitment to DNA damage sites is mediated by the BRCA1-A complex.