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BAK1 Antibodies
AND BAK1 ELISA kits, BAK1 Proteins
Many biological assays use antibodies to detect BAK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BAK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BAK1 antibodies...
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BAK1 Infographic by Boster Bio
All BAK1 Products
Product
Figures
Specificity
Applications
Price
Anti-BAK/BAK1 Antibody Picoband®
2 Citations 4 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9484
100 μg/vial
Cat # PB9484
100 μg/vial
Anti-Bak BAK1 Rabbit Monoclonal Antibody
2 Citations
Human, Mouse
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01163
100 μl
Cat # M01163
100 μl
Human, Mouse
ELISA
$480
Cat # EKC1052
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1052
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01163-1
100 μg/vial
Cat # M01163-1
100 μg/vial
BAK1 Overview
Facts about Bcl-2 homologous antagonist/killer.
Bcl-2 homologous antagonist/killer (BAK1)
Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM.
This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. .
Gene Information
| Human | |
|---|---|
| Gene Name: | BAK1 |
| Uniprot: | Q16611 |
| Entrez: | 578 |
Family
| Belongs to: |
|---|
| Bcl-2 family |
Alternative Names
Apoptosis regulator BAK; BAK; BAK1; BAK-LIKE; BAKMGC3887; BCL2-antagonist/killer 1; BCL2L7; bcl2-L-7; BCL2L7bcl-2 homologous antagonist/killer; BCL2-like 7 protein; Bcl-2-like protein 7; CDN1; MGC117255; pro-apoptotic protein BAK
Molecular Weight
Mass (kDA):
23.409 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.31 |
| Sequence: | 6; NC_000006.12 (33572552..33580296, complement) |
Tissue Specificity
Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Subcellular Localizations
Mitochondrion outer membrane; Single-pass membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Breast
- Leukemia
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
- Lymphoma
- Cell Transformation, Neoplastic
- Malignant Tumor Of Colon
- Melanoma
- Adenocarcinoma
- Lung Neoplasms
Interacting Proteins
- BAX
- BCL2
- BCL2A1
- BCL2L1
- BCL2L2
- BID
- MCL1
- Mcl1
- Mfn1
- Mfn2
Pathways
- Cell Death
- Induction Of Apoptosis
- Programmed Cell Death
- Cell Cycle
- Localization
- Cell Proliferation
- Pathogenesis
- Cell Cycle Arrest
- Rna Interference
- Cell Killing
- Cell Growth
- Mitochondrial Translocation
- Autophagy
PTMs
- Cleavage
- Phosphorylation
- Dephosphorylation
- Methylation
- Oxidation
- Ubiquitination
- Phosphorothioation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BAK1
bosterbio.com/bosterbio-gene-info-cards/BAK1
References
PMID: 7715729 by Farrow S.N., et al. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K.
PMID: 7715730 by Chittenden T., et al. Induction of apoptosis by the Bcl-2 homologue Bak.
2 Publications of Boster BAK1 Antibodies & ELISA Kits
- PubMed ID: 21573215, Minicircle-oriP-IFN?: A Novel Targeted Gene Therapeutic System for EBV Positive ...
- PubMed ID: 15248898, BAK overexpression mediates p53-independent apoptosis inducing effects on human ...
*More publications can be found for each product on its corresponding product page