Homeobox protein Nkx-3.2 Antibodies

AND NKX3-2 ELISA kits, Homeobox protein Nkx-3.2 Proteins

Many biological assays use antibodies to detect Homeobox protein Nkx-3.2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein Nkx-3.2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein Nkx-3.2 antibodies...

We validate the specificity of these antibodies to Homeobox protein Nkx-3.2 by testing them on tissues known to express NKX3-2 positively and negatively. Browse below to find the NKX3-2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NKX3-2 Infographic by Boster Bio

All NKX3-2 Products

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Specificity

Applications

Price

Anti-BAPX1 NKX3-2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A07429
0.1 mg

BAPX1 (NKX3-2) (NM_001189) Human Recombinant Protein

$813
Cat # PROTP78367
20 µg

BAPX1 (NKX3-2) (NM_001189) Human Over-expression Lysate

Human

$628
Cat # LS000579
100 µg

NKX3-2 Overview

Facts about Homeobox protein Nkx-3.2.

NKX3-2 3D structure. Source: alphafold

Homeobox protein Nkx-3.2 (NKX3-2)

Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal gut development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium.

In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity). .

Gene Information

Human
Gene Name:	NKX3-2
Uniprot:	P78367
Entrez:	579

Family

Belongs to:

NK-3 homeobox family

Alternative Names

Bagpipe homeobox protein homolog 1; BAPX1bagpipe homeobox homolog 1 (Drosophila); Homeobox protein NK-3 homolog B; homeobox protein Nkx-3.2; MGC138171; NK3 homeobox 2; NKX3.2; NKX3BSMMD

Molecular Weight

Mass (kDA):
34.814 kDA

Genomic Context


Human

Location:	4p15.33
Sequence:	4; NC_000004.12 (13540830..13544508, complement)

Tissue Specificity

Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton.

Subcellular Localizations

Nucleus.

Diseases

Dysplasia
Hypertrophy
Skeletal Dysplasia
Congenital Absence Of Spleen
Congenital Abnormality
Hypoplasia
Nervousness
Bone Diseases, Developmental
Limb Deformities, Congenital
Cholangiocarcinoma
Sclerosis
Fracture Of First Cervical Vertebra

Hypoxia
Fetal Growth Retardation
Malignant Neoplasms
Dwarfism
Hypoxia-ischemia, Brain
Cerebral Palsy
Hereditary Diseases

Pathways

Ossification
Localization
Endochondral Ossification
Regeneration
Chondrocyte Hypertrophy
Chondrocyte Differentiation
Cartilage Development
Spleen Development
Cell Proliferation
Gastrulation
Pancreas Development
Immune Response
Myelination

Cell Division
Organ Development
Cell Death
Histone Acetylation
Mesoderm Development
Chondroblast Differentiation
Nuclear Import

PTMs

Phosphorylation

Acetylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NKX3-2

References

PMID: 9426254 by Tribioli C., et al. Molecular cloning, chromosomal mapping and developmental expression of BAPX1, a novel human homeobox-containing gene homologous to Drosophila bagpipe.

PMID: 9344671 by Yoshiura K., et al. Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia.