This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
AUH Antibodies
AND AUH ELISA kits, AUH Proteins
Many biological assays use antibodies to detect AUH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AUH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AUH antibodies...
Previous: A1BG
Next: AVP
AUH Infographic by Boster Bio
All AUH Products
Product
Figures
Specificity
Applications
Price
AUH Overview
Facts about Methylglutaconyl-CoA hydratase, mitochondrial.
Methylglutaconyl-CoA hydratase, mitochondrial (AUH)
Catalyzes the conversion of 3-methylglutaconyl-CoA to 3- hydroxy-3-methylglutaryl-CoA (PubMed:11738050, PubMed:12434311, PubMed:12655555). Also has itaconyl-CoA hydratase activity by converting itaconyl-CoA into citramalyl-CoA in the C5- dicarboxylate catabolism pathway (PubMed:29056341).
The C5- dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite (PubMed:29056341). Has very low enoyl-CoA hydratase activity (PubMed:7892223).
Gene Information
| Human | |
|---|---|
| Gene Name: | AUH |
| Uniprot: | Q13825 |
| Entrez: | 549 |
Family
| Belongs to: |
|---|
| enoyl-CoA hydratase/isomerase family |
Alternative Names
3-methylglutaconyl-CoA hydratase; AU RNA binding protein/enoyl-CoA hydratase; AU RNA binding protein/enoyl-Coenzyme A hydratase; AU RNA-binding protein/enoyl-Coenzyme A hydratase; AU-binding protein/enoyl-CoA hydratase; AU-specific RNA-binding enoyl-CoA hydratase; EC 4.2.1.18; methylglutaconyl-CoA hydratase, mitochondrial
Molecular Weight
Mass (kDA):
35.609 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q22.31 |
| Sequence: | 9; NC_000009.12 (91213815..91361969, complement) |
Subcellular Localizations
Mitochondrion.
Diseases
- 3-@methylglutaconic Aciduria, Type I
- Inborn Errors Of Metabolism
- Atrophy
- Leukoencephalopathies
- Speech Delay
- Febrile Convulsions
- Brain Diseases, Metabolic, Inborn
- Infective Disorder
- Cross Infection
- Language Development Disorders
- Metabolic Diseases
- Optic Atrophy
Pathways
- Cell Death
- Excretion
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AUH
bosterbio.com/bosterbio-gene-info-cards/AUH
References
PMID: 7892223 by Nakagawa J., et al. AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity.
PMID: 12434311 by Ijlst L., et al. 3-methylglutaconic aciduria type I is caused by mutations in AUH.