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5 Q&As
Facts about Armadillo repeat-containing X-linked protein 3.
Mitochondrial dynamics and distribution is controlled through ARMCX3 protein degradation, which can be promoted by PCK and negatively controlled by WNT1. Improves the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.
Human | |
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Gene Name: | ARMCX3 |
Uniprot: | Q9UH62 |
Entrez: | 51566 |
Belongs to: |
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eutherian X-chromosome-specific Armcx family |
ALEX3arm protein lost in epithelial cancers, X chromosome, 3; ARM protein lost in epithelial cancers on chromosome X 3; armadillo repeat containing, X-linked 3; armadillo repeat-containing X-linked protein 3,1200004E24Rik; dJ545K15.2; DKFZp781N1954; KIAA0443; MGC12199; Protein ALEX3
Mass (kDA):
42.501 kDA
Human | |
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Location: | Xq22.1 |
Sequence: | X; NC_000023.11 (101623130..101631910) |
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus.
PMID: 11162520 by Kurochkin I.V., et al. ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.