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- Table of Contents
Facts about Rho GTPase-activating protein 5.
Human | |
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Gene Name: | ARHGAP5 |
Uniprot: | Q13017 |
Entrez: | 394 |
Belongs to: |
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No superfamily |
growth factor independent 2; p100 RasGAP-associated p105 protein; p105 RhoGAP; p190-BGFI2; p190BRhoGAP; Rho GTPase activating protein 5; rho GTPase-activating protein 5; RHOGAP5; Rho-type GTPase-activating protein 5
Mass (kDA):
172.46 kDA
Human | |
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Location: | 14q12 |
Sequence: | 14; NC_000014.9 (32072588..32159728) |
Detected in skin fibroblasts (at protein level) (PubMed:8537347).
Cytoplasm. Cell membrane; Peripheral membrane protein. Also membrane-associated in a fibrillar pattern that colocalizes with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.
PMID: 8537347 by Burbelo P.D., et al. p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking.
PMID: 16777052 by Zhan X., et al. Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry.