AKR1B1 Antibodies

AND AKR1B1 ELISA kits, AKR1B1 Proteins

Many biological assays use antibodies to detect AKR1B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKR1B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKR1B1 antibodies...

We validate the specificity of these antibodies to AKR1B1 by testing them on tissues known to express AKR1B1 positively and negatively. Browse below to find the AKR1B1 antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AKR1B1 Infographic by Boster Bio

All AKR1B1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-AKR1B1 Antibody Picoband®

3 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # PB10035
100 μg/vial

Anti-AKR1B1 (K275) Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A01621
100ul

Anti-AKR1B1 monoclonal Antibody

Human

ICC, WB

$482
Cat # M01621
100ul

Anti-Aldose Reductase AKR1B1 Monoclonal Antibody

Canine, Human, Mouse, Rabbit

$380
Cat # M01621-1
100ul

Anti-Aldose reductase AKR1B1 Monoclonal Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # M01621-2
100ul

Human Aldose reductase Recombinant Protein

Enzyme Activity, SDS-PAGE

$234
Cat # PROTP15121
Starting from 20ug

Mouse Aldose reductase/Akr1b1 Recombinant Protein

Enzyme Activity, SDS-PAGE

$250
Cat # PROTP45376
Starting from 20ug

AKR1B1 (NM_001628) Human Over-expression Lysate

Human

$628
Cat # LS000231
100 µg

AKR1B1 Overview

Facts about Aldo-keto reductase family 1 member B1.

AKR1B1 3D structure. Source: alphafold

Aldo-keto reductase family 1 member B1 (AKR1B1)

Catalyzes the NADPH-dependent reduction of a wide array of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. .

Gene Information

Human
Gene Name:	AKR1B1
Uniprot:	P15121
Entrez:	231

Family

Belongs to:

aldo/keto reductase family

Alternative Names

ADR; Aldehyde reductase; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); ALDR1aldose reductase; ALR2; ARaldehyde reductase 1; EC 1.1.1; EC 1.1.1.21; Lii5-2 CTCL tumor antigen; low Km aldose reductase; MGC1804

Molecular Weight

Mass (kDA):
35.853 kDA

Genomic Context


Human

Location:	7q33
Sequence:	7; NC_000007.14 (134442350..134459239, complement)

Tissue Specificity

Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.

Subcellular Localizations

Cytoplasm.

Diseases

Diabetes Mellitus
Malignant Neoplasms
Complications Of Diabetes Mellitus
Neoplasms
Retinal Diseases
Diabetes Mellitus, Non-insulin-dependent
Diabetic Retinopathy
Kidney Diseases
Cataract
Carcinoma
Endometrial Polyp
Diabetic Nephropathy

Diabetes Mellitus, Insulin-dependent
Inflammation
Malignant Neoplasm Of Lung
Hyperglycemia
Malignant Neoplasm Of Liver
Tissue Adhesions

Pathways

Pathogenesis
Embryo Development
Cell Proliferation
Parturition
Transport
Blastocyst Formation
Insemination
Localization
Methylation
Secretion
Fertilization
Inflammatory Response
Menstruation

Translation
Blastocyst Development
Cell Death
Cell Adhesion
Protein Phosphorylation
Response To Lipopolysaccharide
Gene Silencing

PTMs

Reduction
Oxidation
Phosphorylation
Cleavage

Methylation
Nitrosylation
Glycosylation
Prenylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKR1B1

References

PMID: 2498333 by Bohren K.M., et al. The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases.

PMID: 2504709 by Chung S., et al. Cloning and sequence determination of human placental aldose reductase gene.