Agbl4 Antibodies

AND Agbl4 ELISA kits, Agbl4 Proteins

Many biological assays use antibodies to detect Agbl4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Agbl4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Agbl4 antibodies...

We validate the specificity of these antibodies to Agbl4 by testing them on tissues known to express Agbl4 positively and negatively. Browse below to find the Agbl4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Agbl4 Infographic by Boster Bio

All Agbl4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CBCP6 Antibody

6 Q&As

Human

$360
Cat # A14810
100 µl

AGBL4 (NM_032785) Human Over-expression Lysate

Human

$628
Cat # LS084871
100 µg

Agbl4 Overview

Facts about Cytosolic carboxypeptidase 6.

Cytosolic carboxypeptidase 6 (Agbl4)

Metallocarboxypeptidase that mediates deglutamylation of target proteins (PubMed:17244818, PubMed:21074048, PubMed:25103237, PubMed:26829768). Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins (PubMed:17244818).

Also removes polyglutamates from the carboxy-terminus of target proteins like MYLK (PubMed:21074048). Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS (PubMed:26829768).

Gene Information

Mouse
Gene Name:	Agbl4
Uniprot:	Q09LZ8
Entrez:	78933

Family

Belongs to:

peptidase M14 family

Alternative Names

ATP/GTP binding protein-like 4; ATP/GTP-binding protein-like 4; CCP6; cytosolic carboxypeptidase 6; EC 3.4.17.-; FLJ14442

Molecular Weight

Mass (kDA):
62.21 kDA

Genomic Context


Mouse

Location:	4\|4 C7-D1
Sequence:	4;

Tissue Specificity

Widely expressed. Expressed abundantly in testis, pituitary and brain and to a lower extent in eye, stomach, adrenal and kidney. In brain, expressed at low level in cerebellum as compared to cortex.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Agbl4

References

PMID: 17244818 by Kalinina E., et al. A novel subfamily of mouse cytosolic carboxypeptidases.

PMID: 21074048 by Rogowski K., et al. A family of protein-deglutamylating enzymes associated with neurodegeneration.