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- Table of Contents
Facts about Adenylate cyclase type 2.
Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity). .
Human | |
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Gene Name: | ADCY2 |
Uniprot: | Q08462 |
Entrez: | 108 |
Belongs to: |
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adenylyl cyclase class-4/guanylyl cyclase family |
3'-5'-cyclic AMP synthetase; AC2; adenylate cyclase 2 (brain); adenylate cyclase II; adenylate cyclase type 2; Adenylate cyclase type II; Adenylyl cyclase 2; ATP pyrophosphate-lyase 2; EC 4.6.1.1; FLJ45092; HBAC2; KIAA1060FLJ16822; MGC133314; type II adenylate cyclase
Mass (kDA):
123.603 kDA
Human | |
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Location: | 5p15.31 |
Sequence: | 5; NC_000005.10 (7396138..7830081) |
Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Expressed in brain, especially in caudate nucleus, cerebellum and hippocampus.
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm.
PMID: 1427768 by Stengel D., et al. Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.
PMID: 8476432 by Hellevuo K., et al. A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.