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- Table of Contents
Facts about Integrator complex subunit 13.
At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267).
Human | |
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Gene Name: | INTS13 |
Uniprot: | Q9NVM9 |
Entrez: | 55726 |
Belongs to: |
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asunder family |
Integrator complex subunit 13
Mass (kDA):
80.225 kDA
Human | |
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Location: | 12p11.23 |
Sequence: | 12; NC_000012.12 (26905171..26938338, complement) |
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
Nucleus. Cytoplasm. Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M.
PMID: 12601173 by Lee S.-Y., et al. Immunomic analysis of human sarcoma.
PMID: 12414650 by Bourdon V., et al. Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes.