Integrator complex subunit 13 (INTS13)

Crucial regulator of the mitotic cell cycle and development. In prophase, required for dynein anchoring into the nuclear envelope important for appropriate centrosome-nucleus coupling.

At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267).