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- Table of Contents
Facts about Anoctamin-5.
Human | |
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Gene Name: | ANO5 |
Uniprot: | Q75V66 |
Entrez: | 203859 |
Belongs to: |
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anoctamin family |
Anoctamin 5; anoctamin-5; GDD1; Integral Membrane Protein GDD1; LGMD2L; Limb Girdle Muscular Dystrophy 2L (Autosomal Recessive); TMEM16E; Transmembrane Protein 16E
Mass (kDA):
107.188 kDA
Human | |
---|---|
Location: | 11p14.3 |
Sequence: | 11; NC_000011.10 (22192485..22283357) |
Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Colocalized with CALR/calreticulin (PubMed:15124103). Shows an intracellular localization according to PubMed:22075693.
PMID: 15124103 by Tsutsumi S., et al. The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD).
PMID: 15067359 by Katoh M., et al. Identification and characterization of TMEM16E and TMEM16F genes in silico.