Anoctamin-5 Antibodies

AND ANO5 ELISA kits, Anoctamin-5 Proteins

Many biological assays use antibodies to detect Anoctamin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Anoctamin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Anoctamin-5 antibodies...

We validate the specificity of these antibodies to Anoctamin-5 by testing them on tissues known to express ANO5 positively and negatively. Browse below to find the ANO5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANO5 Infographic by Boster Bio

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ANO5 Overview

Facts about Anoctamin-5.

ANO5 3D structure. Source: alphafold

Anoctamin-5 (ANO5)

Does not exhibit calcium-activated chloride channel (CaCC) activity. .

Gene Information

Human
Gene Name:	ANO5
Uniprot:	Q75V66
Entrez:	203859

Family

Belongs to:

anoctamin family

Alternative Names

Anoctamin 5; anoctamin-5; GDD1; Integral Membrane Protein GDD1; LGMD2L; Limb Girdle Muscular Dystrophy 2L (Autosomal Recessive); TMEM16E; Transmembrane Protein 16E

Molecular Weight

Mass (kDA):
107.188 kDA

Genomic Context


Human

Location:	11p14.3
Sequence:	11; NC_000011.10 (22192485..22283357)

Tissue Specificity

Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Colocalized with CALR/calreticulin (PubMed:15124103). Shows an intracellular localization according to PubMed:22075693.

Diseases

Dystrophy
Muscular Dystrophy
Muscular Dystrophies, Limb-girdle
Myopathy
Weakness
Distal Muscular Dystrophies
Miyoshi Myopathy
Muscular Atrophy
Atrophy
Muscle Weakness
Ataxia

Neuromuscular Diseases
Bleeding Tendency
Dysplasia
Osteoarthropathy
Malignant Neoplasms

Pathways

Muscle Atrophy
Transport
Ion Transport
Fluid Transport

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANO5

References

PMID: 15124103 by Tsutsumi S., et al. The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD).

PMID: 15067359 by Katoh M., et al. Identification and characterization of TMEM16E and TMEM16F genes in silico.