TBC1D24 Antibodies

AND TBC1D24 ELISA kits, TBC1D24 Proteins

Many biological assays use antibodies to detect TBC1D24, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TBC1D24 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TBC1D24 antibodies...

We validate the specificity of these antibodies to TBC1D24 by testing them on tissues known to express TBC1D24 positively and negatively. Browse below to find the TBC1D24 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TBC1D24 Infographic by Boster Bio

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TBC1D24 (NM_020705) Human Recombinant Protein

$813
Cat # PROTQ9ULP9
20 µg

TBC1D24 Overview

Facts about TBC1 domain family member 24.

TBC1D24 3D structure. Source: alphafold

TBC1 domain family member 24 (TBC1D24)

May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections growth, probably through a negative modulation of ARF6 function.

Gene Information

Human
Gene Name:	TBC1D24
Uniprot:	Q9ULP9
Entrez:	57465

Family

Belongs to:

No superfamily

Alternative Names

KIAA1171FIME; MGC102885; TBC1 domain family member 24; TBC1 domain family, member 24

Molecular Weight

Mass (kDA):
62.919 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (2475104..2509669)

Tissue Specificity

Highest expression in brain.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cytoplasm. Cytoplasmic vesicle membrane. Mainly cytoplasmatic with partial expression at the plasma membrane (PubMed:20727515). Associates with certain types of membrane phosphoinositides, preferentially those phosphorylated at the D5 position of the inositol ring such as phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity).

Diseases

Epilepsy
Epilepsies, Partial
Dysarthria
Epilepsies, Myoclonic
Nervousness
Epilepsy, Myoclonic, Infantile

Interacting Proteins

ARF6

Pathways

Translation

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TBC1D24

References

PMID: 19077034 by Ishibashi K., et al. Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

PMID: 20727515 by Falace A., et al. TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy.