ABHD12 Antibodies

AND ABHD12 ELISA kits, ABHD12 Proteins

Many biological assays use antibodies to detect ABHD12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABHD12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABHD12 antibodies...

We validate the specificity of these antibodies to ABHD12 by testing them on tissues known to express ABHD12 positively and negatively. Browse below to find the ABHD12 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABHD12 Infographic by Boster Bio

All ABHD12 Products

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Product

Figures

Specificity

Applications

Price

Anti-ABHD12 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A06833
100ul

ABHD12 (NM_001042472) Human Over-expression Lysate

Human

$628
Cat # LS026090
100 µg

ABHD12 Overview

Facts about Lysophosphatidylserine lipase ABHD12.

ABHD12 3D structure. Source: alphafold

Lysophosphatidylserine lipase ABHD12 (ABHD12)

Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a significant LPS lipase from the brain (By similarity).

May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and function as a regulator of endocannabinoid signaling pathways. .

Gene Information

Human
Gene Name:	ABHD12
Uniprot:	Q8N2K0
Entrez:	26090

Family

Belongs to:

serine esterase family

Alternative Names

ABHD12A; abhydrolase domain containing 12; Abhydrolase domain-containing protein 12; BEM46L2; C20orf22; chromosome 20 open reading frame 22; dJ965G21.2; DKFZP434P106; DKFZp434P106,2-arachidonoylglycerol hydrolase; EC 3.1.1.23; monoacylglycerol lipase ABHD12; PHARC

Molecular Weight

Mass (kDA):
45.097 kDA

Genomic Context


Human

Location:	20p11.21
Sequence:	20; NC_000020.11 (25294743..25390835, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Nervousness
Inflammation
Polyneuropathy
Neurodegenerative Disorders
Ataxia
Retinitis Pigmentosa
Cataract
Depressive Disorder
Liver Diseases
Neoplasm Metastasis
Inborn Errors Of Metabolism

Cerebellar Ataxia
Usher Syndrome
Malignant Neoplasms
Pain
Colorectal Cancer
Cytogenetic Abnormality

Pathways

Transport
Synaptic Transmission

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABHD12

References

PMID: 20797687 by Fiskerstrand T., et al. Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism.

PMID: 22969151 by Navia-Paldanius D., et al. Biochemical and pharmacological characterization of human alpha/beta- hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).