Anti-Zinc finger protein 420 ZNF420 Antibody

Product Name

Anti-Zinc finger protein 420 ZNF420 Antibody

View all ZNF420 Antibodies

SKU/Catalog Number

A12954-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Zinc finger protein 420 ZNF420 Antibody catalog # A12954-1. Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Zinc finger protein 420 ZNF420 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12954-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human ZNF420. at AA rangle: 270-350

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12954-1 is reactive to ZNF420 in Human, Mouse

Applications

A12954-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

80247 MW

Background of ZNF420

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of K562 cells using ZNF420 Polyclonal antibody.

Gene/Protein Information For ZNF420 (Source: Uniprot.org, NCBI)

Alternative Names

FLJ20086; KIAA1584; MGC21637; MGC61687; SUHW4; Suppressor of hairy wing homolog 4; zinc finger protein 280D; Zinc finger protein 634; ZNF634suppressor of hairy wing homolog 4 (Drosophila) ZNF420 APAK zinc finger protein 420 zinc finger protein 420|ATM and p53-associated KZNF protein

For more info on ZNF420, check out the ZNF420 Infographic

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In this infographic, you will see the following information for ZNF420: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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