Product Info Summary
SKU: | A03493 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody
View all Cytochrome P450 4A Antibodies
SKU/Catalog Number
A03493
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody (Catalog # A03493). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03493)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human CYTOCHROME P450 4A11/22.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03493 is reactive to CYP4A11 in Human
Reconstitution
Calculated molecular weight
59348 MW
Background of Cytochrome P450 4A
Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).
Capdevila J.H., Arch. Biochem. Biophys. 409:221-227(2003).
Bentley D.R., Nature 441:315-321(2006).
Shin H.D., J. Hum. Genet. 50:259-263(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03493 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from COLO205, HuvEc and HeLa cells, using CYTOCHROME P450 4A11/22 antibody A03493.
Protein Target Info & Infographic
Gene/Protein Information For CYP4A11 (Source: Uniprot.org, NCBI)
Gene Name
CYP4A11
Full Name
Cytochrome P450 4A11
Weight
59348 MW
Superfamily
cytochrome P450 family
Alternative Names
Cytochrome P450 4A11;20-hydroxyeicosatetraenoic acid synthase;20-HETE synthase;CYP4AII;CYPIVA11;Cytochrome P-450HK-omega;Cytochrome P450HL-omega;Fatty acid omega-hydroxylase;Lauric acid omega-hydroxylase;Long-chain fatty acid omega-monooxygenase;1.14.13.205 ;CYP4A11;CYP4A2; CYP4A11 CP4Y, CYP4A2, CYP4AII, CYPIVA11 cytochrome P450 family 4 subfamily A member 11 cytochrome P450 4A11|20-HETE synthase|20-hydroxyeicosatetraenoic acid synthase|P450HL-omega|alkane-1 monooxygenase|cytochrome P-450HK-omega|cytochrome P450, family 4, subfamily A, polypeptide 11|cytochrome P450, subfamily IVA, polypeptide 11|cytochrome P450HL-omega|fatty acid omega-hydroxylase|lauric acid omega-hydroxylase|long-chain fatty acid omega-monooxygenase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CYP4A11, check out the CYP4A11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CYP4A11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody (A03493)
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No publications found for A03493
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Customer Q&As
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5 Customer Q&As for Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody
Question
We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for liver using anti-Cytochrome P450 4A11/22 antibody A03493. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2020-05-04
Answer
Thank you for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2020-05-04
Question
We are currently using anti-Cytochrome P450 4A11/22 antibody A03493 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on monkey tissues as well?
Verified Customer
Verified customer
Asked: 2020-01-21
Answer
The anti-Cytochrome P450 4A11/22 antibody (A03493) has not been validated for cross reactivity specifically with monkey tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2020-01-21
Question
I am interested in to test anti-Cytochrome P450 4A11/22 antibody A03493 on human liver for research purposes, then I may be interested in using anti-Cytochrome P450 4A11/22 antibody A03493 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2019-08-13
Answer
The products we sell, including anti-Cytochrome P450 4A11/22 antibody A03493, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2019-08-13
Question
Does anti-Cytochrome P450 4A11/22 antibody A03493 work for WB with liver?
Verified Customer
Verified customer
Asked: 2019-05-21
Answer
According to the expression profile of liver, CYP4A11 is highly expressed in liver. So, it is likely that anti-Cytochrome P450 4A11/22 antibody A03493 will work for WB with liver.
Boster Scientific Support
Answered: 2019-05-21
Question
Do you have a BSA free version of anti-Cytochrome P450 4A11/22 antibody A03493 available?
Verified Customer
Verified customer
Asked: 2018-03-06
Answer
We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Cytochrome P450 4A11/22 antibody A03493 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2018-03-06