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Product Info Summary
| SKU: | A09478 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-ZIP3 SLC39A3 Antibody
SKU/Catalog Number
A09478
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZIP3 SLC39A3 Antibody (Catalog # A09478). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse.
Storage & Handling
ZIP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZIP3 SLC39A3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09478)
Host
Rabbit
Contents
ZIP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZIP3 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP3. The immunogen is located within amino acids 110 - 160 of ZIP3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TESPA1 antibody is human specific. At least three isoforms TESPA1 are known to exist.
Reactive Species
A09478 is reactive to SLC39A3 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
33601 MW
Background of SLC39A3
The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09478 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZIP3 antibody can be used for detection of ZIP3 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZIP3 in mouse lung tissue lysate with ZIP3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of ZIP3 in mouse lung tissue with ZIP3 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC39A3 (Source: Uniprot.org, NCBI)
Gene Name
SLC39A3
Full Name
Zinc transporter ZIP3
Weight
33601 MW
Superfamily
ZIP transporter (TC 2.A.5) family
Alternative Names
ZIP3, ZIP-3, ZIP3, Zinc transporter ZIP3, Solute carrier family 39 member 3 SLC39A3 ZIP-3, ZIP3 solute carrier family 39 member 3 zinc transporter ZIP3|solute carrier family 39 (zinc transporter), member 3|zrt- and Irt-like protein 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC39A3, check out the SLC39A3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC39A3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZIP3 SLC39A3 Antibody (A09478)
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