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Product Info Summary
| SKU: | A09140-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ZIP2 SLC39A2 Antibody
View all SLC39A2/ZIP2 Antibodies
SKU/Catalog Number
A09140-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZIP2 SLC39A2 Antibody (Catalog # A09140-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ZIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZIP2 SLC39A2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09140-1)
Host
Rabbit
Contents
ZIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZIP2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZIP2. The immunogen is located within amino acids 70 - 120 of ZIP2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of SCUBE3 are known to exist. SCUBE3 antibody is predicted to not cross-react with other SCUBE members
Reactive Species
A09140-1 is reactive to SLC39A2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
32742 MW
Background of SLC39A2/ZIP2
The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09140-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZIP2 antibody can be used for detection of ZIP2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse and rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZIP2 in (A) mouse and (B) rat brain tissue lysate with ZIP2 antibody at 1 μg/mL.
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Immunohistochemistry of ZIP2 in human brain tissue with ZIP2 antibody at 2.5 μg/mL.
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Immunofluorescence of ZIP2 in human brain tissue with ZIP2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC39A2 (Source: Uniprot.org, NCBI)
Gene Name
SLC39A2
Full Name
Zinc transporter ZIP2
Weight
32742 MW
Superfamily
ZIP transporter (TC 2.A.5) family
Alternative Names
6A1, ZIP2, ETI-1, ZIP-2, Zinc transporter ZIP2, 6A1 SLC39A2 6A1, ETI-1, ZIP-2, ZIP2 solute carrier family 39 member 2 zinc transporter ZIP2|Zrt- and Irt-like protein 2|solute carrier family 39 (zinc transporter), member 2|zinc uptake transporter 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC39A2, check out the SLC39A2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC39A2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZIP2 SLC39A2 Antibody (A09140-1)
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