Product Info Summary
SKU: | A08928 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P |
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Product info
Product Name
Anti-ZIP13 SLC39A13 Antibody
SKU/Catalog Number
A08928
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZIP13 SLC39A13 Antibody (Catalog # A08928). Tested in ELISA, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
ZIP13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZIP13 SLC39A13 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08928)
Host
Rabbit
Contents
ZIP13 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZIP13 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human ZIP13. The immunogen is located within amino acids 150 - 200 of ZIP13.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of ZIP13 are known to exist; this antibody will detect both isoforms. ZIP13 antibody is predicted to not cross-react with other ZIP family members.
Reactive Species
A08928 is reactive to SLC39A13 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
39011 MW
Background of Slc39a13
The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08928 is guaranteed for ELISA, IF, IHC-P Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZIP13 Antibody can be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Immunohistochemistry of ZIP13 in human spleen tissue with ZIP13 antibody at 2.5 μg/mL.
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Immunofluorescence of ZIP13 in human spleen tissue with ZIP13 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC39A13 (Source: Uniprot.org, NCBI)
Gene Name
SLC39A13
Full Name
Zinc transporter ZIP13
Weight
39011 MW
Superfamily
ZIP transporter (TC 2.A.5) family
Alternative Names
ZIP13, Zinc transporter ZIP13, LIV-1 subfamily of ZIP zinc transporter 9, LZT-Hs9 Slc39a13|1100001L14Rik, AA387663, ZIP, ZIP-13, ZIP13|solute carrier family 39 (metal ion transporter), member 13|zinc transporter ZIP13|solute carrier family 39 member 13|zrt- and Irt-like protein 13
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC39A13, check out the SLC39A13 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC39A13: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZIP13 SLC39A13 Antibody (A08928)
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