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Product Info Summary
| SKU: | A14403 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Zinc finger protein 536 ZNF536 Antibody
SKU/Catalog Number
A14403
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Zinc finger protein 536 ZNF536 Antibody (Catalog # A14403). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ZNF536 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Zinc finger protein 536 ZNF536 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14403)
Host
Rabbit
Contents
ZNF536 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZNF536 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ZNF536. The immunogen is located within amino acids 30 - 80 of ZNF536.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SIGLEC15 antibody is predicted to not cross-react with other SIGLEC family members.
Reactive Species
A14403 is reactive to ZNF536 in Human, Mouse, Rat
Applications
A14403 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
141417 MW
Background of ZNF536
ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZNF536 antibody can be used for detection of ZNF536 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZNF536 in human brain tissue lysate with ZNF536 antibody at 1 μg/mL.
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Immunohistochemistry of ZNF536 in human brain tissue with ZNF536 antibody at 5 μg/mL.
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Immunofluorescence of ZNF536 in human brain tissue with ZNF536 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ZNF536 (Source: Uniprot.org, NCBI)
Gene Name
ZNF536
Full Name
Zinc finger protein 536
Weight
141417 MW
Superfamily
krueppel C2H2-type zinc-finger protein family
Alternative Names
KIAA0390; zinc finger protein 536 ZNF536 zinc finger protein 536 zinc finger protein 536
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ZNF536, check out the ZNF536 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ZNF536: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Zinc finger protein 536 ZNF536 Antibody (A14403)
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