Anti-YOD1/Otud2 Antibody

Product Name

Anti-YOD1/Otud2 Antibody

View all YOD1 Antibodies

SKU/Catalog Number

A09885

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-YOD1/Otud2 Antibody (Catalog # A09885). Tested in WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-YOD1/Otud2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09885)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human YOD1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A09885 is reactive to YOD1 in Human, Rat

Reconstitution

Calculated molecular weight

38322 MW

Background of YOD1

Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.

Ota T., Nat. Genet. 36:40-45(2004).
Gregory S.G., Nature 441:315-321(2006).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A09885 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For YOD1 (Source: Uniprot.org, NCBI)

Alternative Names

Ubiquitin thioesterase OTU1;3.4.19.12 ;DUBA-8;HIV-1-induced protease 7;HIN-7;HsHIN7;OTU domain-containing protein 2;YOD1;DUBA8, HIN7, OTUD2;PRO0907; YOD1 DUBA8, OTUD2, PRO0907 YOD1 deubiquitinase ubiquitin thioesterase OTU1|DUBA-8|HIN-7|HIV-1-induced protease 7|OTU domain containing 2|OTU domain-containing protein 2|YOD1 OTU deubiquinating enzyme 1 homolog ( yeast)|hsHIN7

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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