Anti-XIAP-associated factor 1 XAF1 Antibody Picoband®

Product Name

Anti-XIAP-associated factor 1 XAF1 Antibody Picoband®

View all XAF1 Antibodies

SKU/Catalog Number

PA1218

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-XIAP-associated factor 1 XAF1 Antibody catalog # PA1218. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-XIAP-associated factor 1 XAF1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1218)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human XAF1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1218 is reactive to XAF1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

34 kDa

Calculated molecular weight

34626 MW

Background of XAF1

XIAP associated factor-1, also known as XAF1, is a human gene. X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells. And alteration in XAF1 and XIAP RNA expression levels may lead to increased apoptotic resistance and proliferation due to unregulated XIAP function in cancer cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1218 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: HEPG2 Whole Cell, HEPG2 Whole Cell
IHC: Human Endometrial Carcinoma Tissue

Validation Images & Assay Conditions

Gene/Protein Information For XAF1 (Source: Uniprot.org, NCBI)

Alternative Names

XIAP-associated factor 1;BIRC4-binding protein;XAF1;BIRC4BP, XIAPAF1; XAF1 BIRC4BP, HSXIAPAF1, XIAPAF1 XIAP associated factor 1 XIAP-associated factor 1|BIRC4-binding protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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