Anti-WWP2 Antibody (N-term)

WWP2 antibody

Boster Bio Anti-WWP2 Antibody (N-term) (Catalog # M03634). Tested in WB application(s). This antibody reacts with Human.

Product Info Summary

SKU: M03634
Size: 80 µl
Reactive Species: Human
Host: Rabbit
Application: WB

Product Name

Anti-WWP2 Antibody (N-term)

View all WWP2 Antibodies

SKU/Catalog Number

M03634

Size

80 µl

Description

Boster Bio Anti-WWP2 Antibody (N-term) (Catalog # M03634). Tested in WB application(s). This antibody reacts with Human.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-WWP2 Antibody (N-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03634)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

This WWP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 218-252 amino acids from the N-terminal region of human WWP2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M03634 is reactive to WWP2 in Human

Applications

M03634 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

98912 Da

Background of WWP2

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation- induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000

Validation Images & Assay Conditions

Gene/Protein Information For WWP2 (Source: Uniprot.org, NCBI)

Gene Name

WWP2

Full Name

NEDD4-like E3 ubiquitin-protein ligase WWP2

Weight

98912 Da

Alternative Names

AIP2Nedd-4-like ubiquitin-protein ligase; atrophin-1 interacting protein 2; Atrophin-1-interacting protein 2; EC 6.3.2; EC 6.3.2.-; NEDD4-like E3 ubiquitin-protein ligase WWP2; WW domain containing E3 ubiquitin protein ligase 2; WW domain-containing protein 2; WWp2-like WWP2 AIP2, WWp2-like WW domain containing E3 ubiquitin protein ligase 2 NEDD4-like E3 ubiquitin-protein ligase WWP2|HECT-type E3 ubiquitin transferase WWP2|atrophin-1 interacting protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on WWP2, check out the WWP2 Infographic

WWP2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for WWP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M03634-80ul

80 µl

$298
M03634-400ul

400 µl

$460

Free Secondary Antibody

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M03634
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$298.00

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