Anti-WAVE2 WASF2 Antibody

Product Name

Anti-WAVE2 WASF2 Antibody

View all WASF2 Antibodies

SKU/Catalog Number

A03969-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-WAVE2 WASF2 Antibody catalog # A03969-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-WAVE2 WASF2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03969-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human WAVE2. at AA rangle: 110-190

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03969-1 is reactive to WASF2 in Human, Mouse, Rat

Applications

A03969-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

54284 MW

Background of WASF2

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Chong J.A.et.al. (1995)Cell 80:949-957
Schoenherr C.J.et.al.(1995)Science 267:1360-1363
Scholl T.et.al.(1996)J. Immunol. 156:1448-1457
Lunyak V.V.et.al. (2002)Science 298:1747-1752

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of 293 cells using WAVE2 Polyclonal antibody.

Gene/Protein Information For WASF2 (Source: Uniprot.org, NCBI)

Alternative Names

IMD2; Protein WAVE-2; SCAR2suppressor of cyclic-AMP receptor (WASP-family); Verprolin homology domain-containing protein 2; WAS protein family, member 2; WASP family Verprolin-homologous protein 2; WAVE2dJ393P12.2; wiskWASP family protein member 2 WASF2 IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2 WASP family member 2 wiskott-Aldrich syndrome protein family member 2|WAS protein family member 2|WASP family Verprolin-homologous protein 2|WASP family protein member 2|WASP family protein member 4|protein WAVE-2|putative Wiskott-Aldrich syndrome protein family member 4|suppressor of cyclic-AMP receptor (WASP-family)|verprolin homology domain-containing protein 2

For more info on WASF2, check out the WASF2 Infographic

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In this infographic, you will see the following information for WASF2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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