WASF2 Antibodies

AND WASF2 ELISA kits, WASF2 Proteins

Many biological assays use antibodies to detect WASF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WASF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WASF2 antibodies...

We validate the specificity of these antibodies to WASF2 by testing them on tissues known to express WASF2 positively and negatively. Browse below to find the WASF2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WASF2 Infographic by Boster Bio

All WASF2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-WASF2 Antibody

Human

IHC, WB

$360
Cat # A03969
100 µl

Anti-WAVE2 WASF2 Antibody

3 Q&As

Human, Mouse, Rat

$399
Cat # A03969-1
100μl

Anti-WASF2 Rabbit Monoclonal Antibody

1 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # M03969
100 μl

Anti-WASF2 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03969-2
100ul

WASF2 (NM_006990) Human Recombinant Protein

$1249
Cat # PROTQ9Y6W5
20 µg

WASF2 (NM_006990) Human Over-expression Lysate

Human

$628
Cat # LS010163
100 µg

WASF2 Overview

Facts about Wiskott-Aldrich syndrome protein family member 2.

WASF2 3D structure. Source: alphafold

Wiskott-Aldrich syndrome protein family member 2 (WASF2)

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments.

Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

Gene Information

Human
Gene Name:	WASF2
Uniprot:	Q9Y6W5
Entrez:	10163

Family

Belongs to:

SCAR/WAVE family

Alternative Names

IMD2; Protein WAVE-2; SCAR2suppressor of cyclic-AMP receptor (WASP-family); Verprolin homology domain-containing protein 2; WAS protein family, member 2; WASP family Verprolin-homologous protein 2; WAVE2dJ393P12.2; wiskWASP family protein member 2

Molecular Weight

Mass (kDA):
54.284 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (27404230..27490167, complement)

Tissue Specificity

Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, lamellipodium. At the interface between the lamellipodial actin meshwork and the membrane.

Diseases

Wiskott-aldrich Syndrome
Malignant Neoplasms
Neoplasm Metastasis
Neoplasms
Cell Invasion
Protrusion
Neoplasm Invasiveness
Carcinoma
Melanoma
Malignant Neoplasm Of Breast
Tissue Adhesions
Mammary Neoplasms

Melanoma, Experimental
Lung Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node
Immunologic Deficiency Syndromes
Adenocarcinoma
Malignant Paraganglionic Neoplasm

Interacting Proteins

ZDHHC17

Pathways

Cell Migration
Localization
Rna Interference
Cell Motility
Chemotaxis
Transport
Cell Proliferation
Cell Activation
T Cell Activation
Proteolysis
Platelet Aggregation
Phagocytosis
Actin Nucleation

Wound Healing
Actin Cytoskeleton Reorganization
Macrophage Chemotaxis
Conjugation
Pathogenesis
Cell Adhesion
Aging

PTMs

Phosphorylation
Cleavage

Prenylation
Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WASF2

References

PMID: 10381382 by Suetsugu S., et al. Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex.

PMID: 11130076 by Miki H., et al. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling.