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Product Info Summary
| SKU: | A00691 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-VAV1 (Ab-174) Antibody
SKU/Catalog Number
A00691
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-VAV1 (Ab-174) Antibody (Catalog # A00691). Tested in WB, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-VAV1 (Ab-174) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00691)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00691 is reactive to VAV1 in Human
Reconstitution
Calculated molecular weight
98314 MW
Background of Vav-1
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Ana V. Miletic, J. Biol. Chem., Dec 2006; 281: 38257 - 38265.
Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003; 23: 6291 - 6299.
Vered Schapira, Cancer Res., Jun 2006; 66: 6183 - 6191.
Maya Groysman, J. Biol. Chem., Dec 2002; 277: 50121 - 50130.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00691 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
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Western blot analysis of extracts from Jurkat cells, using VAV1 (Ab-174) antibody A00691.
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Western blot analysis of extracts from JK cells (Lane 2), using VAV1 (Ab-174) antiobdy A00691. The lane on the left is treated with synthesized peptide.
Protein Target Info & Infographic
Gene/Protein Information For VAV1 (Source: Uniprot.org, NCBI)
Gene Name
VAV1
Full Name
Proto-oncogene vav
Weight
98314 MW
Alternative Names
Proto-oncogene vav;VAV1;VAV; VAV1 VAV vav guanine nucleotide exchange factor 1 proto-oncogene vav|vav 1 guanine nucleotide exchange factor|vav 1 oncogene
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on VAV1, check out the VAV1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for VAV1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-VAV1 (Ab-174) Antibody (A00691)
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No publications found for A00691
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