Product Info Summary
SKU: | A15678 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-TYW3 Antibody
SKU/Catalog Number
A15678
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TYW3 Antibody (Catalog # A15678). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
TYW3 antibody can be stored at 4 °C, stable for one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TYW3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15678)
Host
Rabbit
Contents
TYW3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TYW3 antibody was raised against a 17 amino acid synthetic peptide near the center of human TYW3. The immunogen is located within amino acids 160 - 210 of TYW3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist; this antibody will detect both isoforms.
Reactive Species
A15678 is reactive to TYW3 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
29794 MW
Background of TYW3
TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A15678 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TYW3 antibody can be used for detection of TYW3 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of TYW3 in A549 cell lysate with TYW3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Protein Target Info & Infographic
Gene/Protein Information For TYW3 (Source: Uniprot.org, NCBI)
Gene Name
TYW3
Full Name
tRNA wybutosine-synthesizing protein 3 homolog
Weight
29794 MW
Superfamily
TYW3 family
Alternative Names
C1orf171, C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3 TYW3 C1orf171 tRNA-yW synthesizing protein 3 homolog tRNA wybutosine-synthesizing protein 3 homolog|tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase|tRNA-yW-synthesizing protein 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TYW3, check out the TYW3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TYW3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TYW3 Antibody (A15678)
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