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Product Info Summary
| SKU: | A14252 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-TRIM58 Antibody
SKU/Catalog Number
A14252
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TRIM58 Antibody (Catalog # A14252). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TRIM58 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TRIM58 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14252)
Host
Rabbit
Contents
TRIM58 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TRIM58 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRIM58.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CHADL antibody is human, mouse and rat reactive. CHADL antibody is predicted to not cross-react with Chondroadherin protein.
Reactive Species
A14252 is reactive to TRIM58 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
54766 MW
Background of TRIM58
TRIM58 is a member of the tripartite motif-containing family of proteins that frequently possess E3 ubiquitin ligase activities (1). TRIM58 is strongly expressed in erythroid lineage cells and is further upregulated during late erythroid maturation. Recent experiments suggest that TRIM58 facilitates erythroblast enucleation by ubiquitinating the intermediate chain of the microtubule motor dynein, thereby inducing proteolytic degradation (2).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A14252 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TRIM58 antibody can be used for Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TRIM58 in (A) human heart tissue and (B) mouse kidney lysate with TRIM58 antibody at 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TRIM58 (Source: Uniprot.org, NCBI)
Gene Name
TRIM58
Full Name
E3 ubiquitin-protein ligase TRIM58
Weight
54766 MW
Superfamily
TRIM/RBCC family
Alternative Names
Tripartite motif containing 58 protein, BIA2 TRIM58 BIA2 tripartite motif containing 58 E3 ubiquitin-protein ligase TRIM58|RING-type E3 ubiquitin transferase TRIM58|tripartite motif-containing protein 58
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TRIM58, check out the TRIM58 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TRIM58: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TRIM58 Antibody (A14252)
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No publications found for A14252
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