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Product Info Summary
| SKU: | A03541 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Transmembrane protein 106B TMEM106B Antibody
SKU/Catalog Number
A03541
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Transmembrane protein 106B TMEM106B Antibody (Catalog # A03541). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
TMEM106B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Transmembrane protein 106B TMEM106B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03541)
Host
Rabbit
Contents
TMEM106B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TMEM106B antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TMEM106B. The immunogen is located within the first 50 amino acids of TMEM106B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This TMEM106B antibody is predicted to have no cross-reactivity to TMEM106A.
Reactive Species
A03541 is reactive to TMEM106B in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
31127 MW
Background of TMEM106B
Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03541 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TMEM106B antibody can be used for detection of TMEM106B by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TMEM106B in human brain tissue lysate with TMEM106B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of TMEM106B in human liver tissue with TMEM106B antibody at 2.5 μg/mL.
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Immunofluorescence of TMEM106B in human liver tissue with TMEM106A antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TMEM106B (Source: Uniprot.org, NCBI)
Gene Name
TMEM106B
Full Name
Transmembrane protein 106B
Weight
31127 MW
Superfamily
TMEM106 family
Alternative Names
Transmembrane protein 106B TMEM106B HLD16 transmembrane protein 106B transmembrane protein 106B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMEM106B, check out the TMEM106B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMEM106B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Transmembrane protein 106B TMEM106B Antibody (A03541)
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