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Product Info Summary
| SKU: | A00758 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Transcription factor SOX-10 SOX10 Antibody
SKU/Catalog Number
A00758
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Transcription factor SOX-10 SOX10 Antibody (Catalog # A00758). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SOX10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Transcription factor SOX-10 SOX10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00758)
Host
Rabbit
Contents
SOX10 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SOX10 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human SOX10.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SOX10 Antibody is predicted to not cross-react with other SOX familiy members.
Reactive Species
A00758 is reactive to SOX10 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
49911 MW
Background of SOX10
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and the determination of the cell fate (1). The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins (2). This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development (2). Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschprung disease (3). SLC30A8 expression in beta-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00758 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SOX10 antibody can be used for Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SOX10 in rat heart tissue lysate with SOX10 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of SOX10 in rat heart tissue with SOX10 Antibody at 5 μg/mL.
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Immunofluorescence of SOX10 in rat heart tissue with SOX10 Antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SOX10 (Source: Uniprot.org, NCBI)
Gene Name
SOX10
Full Name
Transcription factor SOX-10
Weight
49911 MW
Alternative Names
SRY (sex determining region Y)-box 10, DOM,WS4, PCWH, WS2E, WS4C SOX10 DOM, PCWH, WS2E, WS4, WS4C SRY-box transcription factor 10 transcription factor SOX-10|SRY (sex determining region Y)-box 10|SRY-box 10|SRY-related HMG-box gene 10|dominant megacolon, mouse, human homolog of
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SOX10, check out the SOX10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SOX10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Transcription factor SOX-10 SOX10 Antibody (A00758)
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