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Key=sku, value=A00198-1
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Key=created_at, value=2020-03-11 06:18:47
Key=updated_at, value=2024-09-26 01:02:56
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Key=name, value=Anti-Toll-like receptor 9 TLR9 Antibody
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Key=meta_title, value=Toll-like receptor 9 TLR9 Antibody A00198-1
Key=meta_description, value=Boster Bio Anti-Toll-like receptor 9 TLR9 Antibody (Catalog # A00198-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse. Supplied as 0.1 mg in Liquid form antibody.
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Key=url_key, value=anti-toll-like-receptor-9-tlr9-antibody-a00198-1-boster
Key=url_path, value=anti-il-8-antibody-a00423-boster
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Key=image_label, value=Western blot analysis of IL-8 expression in Recombinant Human IL-8 50ng (lane 1). IL-8 at 11KD was detected using rabbit anti-IL-8 Antigen Affinity purified polyclonal antibody (Catalog # A00423) at 1:1000. The blot was developed using chemiluminescence (
Key=small_image_label, value=Western blot analysis of IL-8 expression in Recombinant Human IL-8 50ng (lane 1). IL-8 at 11KD was detected using rabbit anti-IL-8 Antigen Affinity purified polyclonal antibody (Catalog # A00423) at 1:1000. The blot was developed using chemiluminescence (
Key=thumbnail_label, value=Western blot analysis of IL-8 expression in Recombinant Human IL-8 50ng (lane 1). IL-8 at 11KD was detected using rabbit anti-IL-8 Antigen Affinity purified polyclonal antibody (Catalog # A00423) at 1:1000. The blot was developed using chemiluminescence (
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Key=size, value=0.1 mg
Key=protein_name, value=Toll-like receptor 9
Key=gene_full_name, value=Toll-like receptor 9
Key=uniprot_id, value=Q9NR96
Key=sensitivity
Key=applications, value=ELISA, IF, IHC-P, WB
Key=reactivity, value=Human, Mouse
Key=form, value=Liquid
Key=concentration, value=1 mg/mL
Key=cross_reactivity, value=ITCH antibody is human, mouse and rat reactive. At least three isoforms of ITCH are known to exist; this antibody only recognizes the two longest isoforms. This antibody is predicted to not cross-react with other members of the Nedd4 protein family.
Key=clone_number
Key=predicted_reactivity, value=Bovine, Pig, Sheep
Key=source_company, value=Prosci 3737; Cost: 249
Key=isotype, value=IgG
Key=molecular_weight, value=115860 MW
Key=sample_size_available, value=25ug for $99, contact us for details
Key=related_product_skus, value=EK0413,PB9621,PROTP10145,PROTP10145-1,PROTP10145-2,PROTP10145-3,PROTP19874,PROTP26894,PROTP41324,PROTP67813
Key=product_category, value=Primary Antibodies
Key=research_category, value=Innate Immunity, Signal Transduction
Key=clonality, value=Polyclonal
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Key=cj_related_products, value=B Cell Proliferation:M00068-1|A02853^Communicable Diseases:PB9207^Cytokine Research:PA1211^Macrophage Activation:EK1561^Systemic Infection:PA1700
Key=description, value=Boster Bio Anti-Toll-like receptor 9 TLR9 Antibody (Catalog # A00198-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Key=short_description, value=Boster Bio Anti-Toll-like receptor 9 TLR9 Antibody (Catalog # A00198-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Key=meta_keyword, value=Anti-Toll-like receptor 9 TLR9 Antibody
Key=contents, value=TLR9 Antibody is supplied in PBS containing 0.02% sodium azide.
Key=background, value=Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TLR9 is strictly dependent on MyD88.
Key=gene_name, value=TLR9
Key=synonyms, value=CD289, Toll-like receptor 9
Key=application_details, value=TLR9 antibody can be used for detection of TLR9 by Western blot at 0.5 to 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Key=subcellular_localization, value=Endoplasmic reticulum membrane
Key=tissue_specificity, value=Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.
Key=protein_function, value=Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:11564765, PubMed:17932028). Controls lymphocyte response to Helicobacter infection (By similarity). Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (PubMed:23857366).
Key=application_notes
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Key=competitor_equivalent_skus, value=sc 25342|sc 55462|sc 7165|sc 4600|sc 73321|sc 7922|sc 1269|sc 376750|sc 8427|sc 7302|sc 52870|sc 101499|sc 32817|sc 71367
Key=immunogen, value=TLR9 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human TLR9. The immunogen is located within amino acids 960 - 1010 of TLR9.
Key=purification, value=TLR9 Antibody is affinity chromatography purified via peptide column.
Key=storage, value=TLR9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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