Anti-TNFAIP8L3 Antibody

Product Name

Anti-TNFAIP8L3 Antibody

View all Tnfaip8l3 Antibodies

SKU/Catalog Number

PA2257

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-TNFAIP8L3 Antibody catalog # PA2257. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TNFAIP8L3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2257)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human TNFAIP8L3, different from the related mouse and rat sequences by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2257 is reactive to TNFAIP8L3 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

33 kDa

Calculated molecular weight

32659 MW

Background of Tnfaip8l3

TNFAIP8L3 belongs to the TNFAIP8 family. It acts as a negative mediator of apoptosis and may play a role in tumor progression. This gene suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2257 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: MCF-7 Whole Cell, SW620 Whole Cell, COS7 Whole Cell, SKOV Whole Cell, JURKAT Whole Cell
IHC: Human Intestinal Cancer Tissue, Human Mammary Cancer Tissue

Validation Images & Assay Conditions

Gene/Protein Information For TNFAIP8L3 (Source: Uniprot.org, NCBI)

Alternative Names

Tumor necrosis factor alpha-induced protein 8-like protein 3;TNF alpha-induced protein 8-like protein 3;TNFAIP8-like protein 3;TNFAIP8L3;

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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