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Key=sku, value=PA1385
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Key=created_at, value=2014-08-05 15:18:35
Key=updated_at, value=2024-10-19 05:02:47
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody Picoband®
Key=cj_search_index
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Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-Metalloproteinase Inhibitor 1 TIMP1 Antibody PA1385 | Boster Bio
Key=meta_description, value=Rabbit Anti-Metalloproteinase Inhibitor 1 TIMP1 Antibody PA1385 that detects TIMP1 by IHC, WB. Tested in Human, 10 citations. Order now!
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Key=image_label, value=Anti-TIMP-1 antibody, PA1385, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Key=small_image_label, value=Anti-TIMP-1 antibody, PA1385, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Key=thumbnail_label, value=Anti-TIMP-1 antibody, PA1385, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=100 μg/vial
Key=protein_name, value=Metalloproteinase inhibitor 1
Key=gene_full_name, value=Metalloproteinase inhibitor 1
Key=uniprot_id, value=P01033
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=IHC, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=source_company, value=Boster PA1385
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=23171 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Angiogenesis, Cancer, Cardiovascular, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Protease Inhibitors, Proteolysis/Ubiquitin, Signal Transduction
Key=clonality, value=Polyclonal
Key=swatch_image, value=/antibody/ek0583-2-ELISA-rat-timp-1-picokine-elisa-kit.jpg
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Key=cj_related_products, value=Hepatic Fibrosis:PB9702|EKC1528|A00059T179|EK0513|EK0520^Liver Cirrhosis:A01283-1
Key=description, value=Boster Bio Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody catalog # PA1385. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody catalog # PA1385. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody
Key=contents, value=Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Key=background, value=TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).
Key=gene_name, value=TIMP1
Key=synonyms, value=Metalloproteinase inhibitor 1;Erythroid-potentiating activity;EPA;Fibroblast collagenase inhibitor;Collagenase inhibitor;Tissue inhibitor of metalloproteinases 1;TIMP-1;TIMP1;CLGI, TIMP;
Key=application_details, value=Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Key=subcellular_localization, value= Secreted .
Key=sequence_similarities, value=Belongs to the protease inhibitor I35 (TIMP) family.
Key=tissue_specificity, value= Detected in rheumatoid synovial fluid (at protein level). .
Key=protein_function, value= Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. .
Key=application_notes, value=Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 1310|sc 21734|sc 365905|sc 5290|sc 5538|sc 56489|sc 58435|sc 6832|sc 6832 R|sc 7956|sc 80995
Key=immunogen, value=A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP-1.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=23 kDa
Key=custom_attribute_2, value=WB: human U-87MG whole cell, human U2OS whole cell, human PC-3 whole cell
IHC: Human Mammary Cancer Tissue
Key=custom_attribute_3, value=BA0575
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