Product Info Summary
SKU: | A02004 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-TBC1 domain family member 4 TBC1D4 Antibody
SKU/Catalog Number
A02004
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TBC1 domain family member 4 TBC1D4 Antibody (Catalog # A02004). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
Storage & Handling
TBC1D4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-TBC1 domain family member 4 TBC1D4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02004)
Host
Rabbit
Contents
TBC1D4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TBC1D4 antibody was raised against an 19 amino acid peptide near the carboxy terminus of human TBC1D4 . The immunogen is located within amino acids 1190 - 1240 of TBC1D4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist; this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.
Reactive Species
A02004 is reactive to TBC1D4 in Human
Applications
A02004 is guaranteed for ELISA, IHC-P Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
146563 MW
Background of TBC1D4
TBC1D4, also known as the Akt substrate AS160, was initially identified as an Akt substrate containing a GTPase-activating domain that regulates GLUT4 trafficking, with activation following insulin stimulation. TBC1D4 truncations in humans is a major cause of dominant inherited insulin resistance. The loss of TBC1D4 results in the accumulation of GLUT4 in compartments that are primed for fusion in basal adipocytes.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TBC1D4 antibody can be used for immunohistochemistry starting at 10 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry of TBC1D4 in human prostate tissue with TBC1D4 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TBC1D4 (Source: Uniprot.org, NCBI)
Gene Name
TBC1D4
Full Name
TBC1 domain family member 4
Weight
146563 MW
Alternative Names
Akt substrate of 160 kDa; AS160Acrg embryonic lethality minimal region ortholog; DKFZp779C0666; KIAA0603TBC (Tre-2, BUB2, CDC16) domain-containing protein; TBC1 domain family member 4; TBC1 domain family, member 4 TBC1D4 AS160, NIDDM5 TBC1 domain family member 4 TBC1 domain family member 4|TBC (Tre-2, BUB2, CDC16) domain-containing protein|akt substrate of 160 kDa
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TBC1D4, check out the TBC1D4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TBC1D4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TBC1 domain family member 4 TBC1D4 Antibody (A02004)
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