Anti-TAF1B Antibody

Product Name

Anti-TAF1B Antibody

View all TAF1B Antibodies

SKU/Catalog Number

A06986

Size

100ul

Form

Liquid

Description

Boster Bio Anti-TAF1B Antibody catalog # A06986. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TAF1B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06986)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

A synthetic peptide corresponding to residues in Human RGMB

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06986 is reactive to TAF1B in Human

Applications

A06986 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

68832 MW

Background of TAF1B

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Celeste A.J., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
Mazerbourg S., J. Biol. Chem. 280:32122-32132(2005).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For TAF1B (Source: Uniprot.org, NCBI)

Alternative Names

RAF1BTATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD; RAFI63MGC:9349; RNA polymerase I-specific TBP-associated factor 63 kDa; SL1SL1, 63kD subunit; TAFI63TBP-associated factor 1B; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa; TATA box-binding protein-associated factor 1B; TATA box-binding protein-associated factor RNA polymerase I subunit B; Transcription initiation factor SL1/TIF-IB subunit B TAF1B MGC:9349, RAF1B, RAFI63, SL1, TAFI63 TATA-box binding protein associated factor, RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit B|RNA polymerase I-specific TBP-associated factor 63 kDa|SL1, 63kD subunit|TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD|TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa|TATA box-binding protein-associated factor 1B|TATA-box binding protein associated factor, RNA polymerase I, B|TBP-associated factor 1B|transcription initiation factor SL1/TIF-IB subunit B

For more info on TAF1B, check out the TAF1B Infographic

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In this infographic, you will see the following information for TAF1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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