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Product Info Summary
| SKU: | A02952 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-TACI TNFRSF13B Antibody
View all TACI/TNFRSF13B/CVID Antibodies
SKU/Catalog Number
A02952
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TACI TNFRSF13B Antibody (Catalog # A02952). Tested in ELISA, WB, ICC applications. This antibody reacts with Human.
Storage & Handling
TACI antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TACI TNFRSF13B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02952)
Host
Rabbit
Contents
TACI Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TACI antibody was raised against a synthetic peptide mapping at the amino terminus of human TACI. The immunogen is located within the first 50 amino acids of TACI.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ANGPTL3 antibody is human, mouse and rat reactive. ANGPTL3 antibody is predicted not to cross-react with other ANGPTL family proteins.
Reactive Species
A02952 is reactive to TNFRSF13B in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
31816 MW
Background of TACI/TNFRSF13B/CVID
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-κB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02952 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TACI polyclonal antibody can be used for detection of TACI by Western blot at 5 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TACI in K562 (A) and U937 (B) cell lysates with TACI antibody at 5 μg/mL.
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Immunocytochemistry of TACI in K562 cells with TACI antibody at 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TNFRSF13B (Source: Uniprot.org, NCBI)
Gene Name
TNFRSF13B
Full Name
Tumor necrosis factor receptor superfamily member 13B
Weight
31816 MW
Alternative Names
CVID, RYZN, TACI, CD267, CVID2, TNFRSF14B, Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor TNFRSF13B CD267, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B TNF receptor superfamily member 13B tumor necrosis factor receptor superfamily member 13B|transmembrane activator and CAML interactor|tumor necrosis factor receptor 13B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TNFRSF13B, check out the TNFRSF13B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TNFRSF13B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TACI TNFRSF13B Antibody (A02952)
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